KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPHA2
All Species:
18.18
Human Site:
S426
Identified Species:
44.44
UniProt:
P29317
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29317
NP_004422.2
976
108266
S426
S
G
L
V
T
S
R
S
F
R
T
A
S
V
S
Chimpanzee
Pan troglodytes
P0C0K6
1020
110674
S466
V
Q
A
V
N
G
V
S
E
L
S
P
D
P
P
Rhesus Macaque
Macaca mulatta
NP_001035768
976
108217
S426
S
G
L
V
T
S
R
S
F
R
T
A
S
V
S
Dog
Lupus familis
XP_544546
975
108247
S426
S
E
L
V
A
S
R
S
F
R
T
A
S
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q03145
977
108805
S427
S
G
L
V
T
S
R
S
F
R
T
A
S
V
S
Rat
Rattus norvegicus
P54757
1005
110989
R457
S
D
L
S
P
G
T
R
Q
Y
V
S
V
N
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519951
973
108448
S424
S
G
F
V
T
T
R
S
F
R
T
A
S
V
S
Chicken
Gallus gallus
P54755
1013
112227
R431
S
D
Q
N
P
G
A
R
Q
F
V
S
V
N
V
Frog
Xenopus laevis
Q91845
986
109822
D426
S
K
Q
N
P
G
Q
D
Q
A
V
S
V
T
V
Zebra Danio
Brachydanio rerio
O13146
981
109636
R429
S
D
L
S
P
S
P
R
Q
L
V
S
V
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.9
97.7
94.7
N.A.
92.6
50.6
N.A.
84.8
52.2
52.5
50.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
57.7
98.2
96.9
N.A.
95.2
66
N.A.
90.7
68
68.6
68
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
86.6
N.A.
100
13.3
N.A.
86.6
6.6
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
86.6
N.A.
100
20
N.A.
93.3
13.3
20
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
10
0
0
10
0
50
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
30
0
0
0
0
0
10
0
0
0
0
10
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
50
10
0
0
0
0
0
% F
% Gly:
0
40
0
0
0
40
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
60
0
0
0
0
0
0
20
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
20
10
0
0
0
0
0
0
0
0
30
0
% N
% Pro:
0
0
0
0
40
0
10
0
0
0
0
10
0
10
10
% P
% Gln:
0
10
20
0
0
0
10
0
40
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
50
30
0
50
0
0
0
0
0
% R
% Ser:
90
0
0
20
0
50
0
60
0
0
10
40
50
0
50
% S
% Thr:
0
0
0
0
40
10
10
0
0
0
50
0
0
10
0
% T
% Val:
10
0
0
60
0
0
10
0
0
0
40
0
40
50
40
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _